Diagnostic Pathology: Familial Cancer Syndromes

This expert volume in the Diagnostic Pathology series is an up-to-date, comprehensive diagnostic support tool for pathologists, oncologists, and other physicians who diagnose and treat patients with cancer. An excellent point-of-care reference for practitioners at all levels of experience and training, the third edition of Diagnostic Pathology: Familial Cancer Syndromes offers clinically useful information on hereditary cancer syndromes, including differential diagnosis and management. Richly illustrated and easy to use, this volume is ideal as a one-stop resource for day-to-day reference or as a reliable training tool.

• Helps physicians recognize syndromes and syndrome-associated neoplasms and advise treating physicians, patients, and their families on the possibility of a familial syndrome and their risk of developing other tumors
• Addresses a wide range of inherited tumor syndromes to increase understanding of the gross and histologic features of syndromic-associated neoplasms as well as associated manifestations
• Part I includes nearly 100 detailed chapters describing diagnoses by organ and system associated with familial cancer syndromes; Part II contains more than 80 chapters with detailed descriptions of major inherited syndromes (cross-referenced with diagnoses); and Part III features an updated Molecular Factors Index that includes a complete description of each known gene associated with a familial cancer syndrome
• Includes substantial updates throughout, with more than a dozen new chapters, new images and references, updated guidelines and classifications based on the 2025 WHO Classification of Tumours: Genetic Tumour Syndromes, details on the newest familial cancer syndromes, and more
• Contains hundreds of tables organized by body part and/or organ system that include selected existing genetic and familial cancers and identified associated genes, clinical features, recognized manifestations, and staging images/microscopic examples
• Features nearly 2,300 print and online images, including clinical and radiologic images, algorithms, graphics, gross pathology and histology images, and a wide range of special and immunohistochemical stains and molecular markers?all carefully annotated to highlight the most diagnostically significant factors
• Employs consistently templated chapters, bulleted content, key facts, annotated images, and an extensive index for quick, expert reference at the point of care
• Includes an version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional dgtl ancillary content may publish up to 6 weeks following the publication date